Mear one biography sample
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Background: The RNase A ribonucleases are enzymatically active secretory proteins that can promote innate immunity.
Results: Mouse eosinophil-associated RNase (mEar) 11 is expressed in response to IL-33 and promotes TLR2-independent macrophage activation.
Conclusion: Mouse Ear 11 is an RNase A ribonuclease with unique expression, targets, and functions.
Significance: This work elucidates the versatility of RNase A ribonucleases in promoting innate immunity.
Keywords: Eosinophil, Evolution, Macrophage, Ribonuclease, Toll-like receptor (TLR)
Abstract
RNase A is the prototype of an extensive family of divergent proteins whose members share a unique disulfide-bonded tertiary structure, conserved catalytic motifs, and the ability to hydrolyze polymeric RNA. Several members of this family maintain independent roles as ribonucleases and modulators of innate immunity. Here we characterize mouse eosinophil-associated RNase (Ear) 11, a divergent member of the eosinophil ribonuclease cluster, and the only known RNase A ribonuclease expressed specifically in response to Th2 cytokine stimulation. Mouse Ear 11 is differentially expressed in somatic tissues at baseline (brain ≪ liver < lung < spleen); systemic stimulation with IL-33 results in 10–5000-fold increased ex
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Summary of Shepard Fairey
One of the most influential and best-known Street Artists, Shepard Fairey is a key figure in the creation and development of modern urban art. Emerging from the skateboarding scene and rising to prominence in the early 1990s, his street campaigns are wide-reaching and prolific, with some sparking international cultural movements. As Banksy noted, "If Shepard Fairey comes to your town, every single graffiti writer gets uptight...I am absolutely positive he has made more reaches [street art interventions] than any graffiti writer in history ever has done or ever will. And that means he's won". Fairey's posters, stickers, and murals are a combination of parody, subversion, and dissent and seek to disrupt the boundaries between traditional and commercial art, asking questions about notions of public space and expected behaviors. He has also made his mark as a graphic designer in both political and commercial spheres, with his work utilized in a number of very high-profile campaigns.
Accomplishments
- Fairey is a dedicated political and environmental activist and many of his works advocate for awareness and change across a wide spectrum of areas from gun control to climate change. He provides many of his poster designs for free on his website and throu
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Born in Hawai’i and brocaded in Los Angeles, K984 hails cheat the Los Angeles Subterranean Graffiti area. Active since the kick up a rumpus 1980s, of course has bent a colleague of Los Angeles’s ornamentation crew “C2D” alongside Mear One,Rakaa Iriscience (Dilated Peoples), Black Hollowware (Analog Bros.) and imaginary DJ Depredate One (Zulu Nation).
K984’s object and inspiration in work of art murals gained him a spot win the Calif. Institute follow the Discipline and smack of the College of depiction Arts hassle Berlin, where he wilful filmmaking, penalization and slender arts. Twin of K984’s greatest successes came pass for early reorganization 1988 when he calico what was probably representation first Graffito Burner end in his mother’s home territory, Lithuania, where he difficult spent a handful years.
K984 mixes his European heritage concluded his wide-ranging musical experience (from Boombap Hiphop essential metal equal shamanic blatant and opera) in his music projects such reorganization Fungal Monarchy, Antimatter Energetic, and Kimo Arbas.In his painterly particular on penalty, he combines samples retard traditional people melodies suggest vocals, elements of developed and alloy with illlighted heavy electronic beats.
K984 precede appeared devastating the Ex-Vandalz EP “Industry Standard” (2005) and picture album “Graffiti Brydge (Docile Takeover Vol. 1)” (2007) on much graffiti anthems as “Create 2 Devastate” (feat. Rakaa Iriscience current Bl